general interest

Disease-associated mutations can be prognostic of outcome and inform treatment choices. However, traditional tissue biopsies limit the ability to implement personalized treatments. Read about how multiplex digital PCR can enable the tracking of treatment efficacy using liquid biopsies.

Gene augmentation and antisense therapies treat disease by providing a functional copy of faulty gene or repressing its expression. Find out how gene editing tools, like CRISPR, promise a more permanent cure.

In this fourth and final part of the series on assessing the health of your cells, we review the different stages of necroptosis, see how it differs from apoptosis, and learn about the various methods of assessing cellular necroptosis.

Find out why fluorescent western blotting is gaining in popularity and how it compares to more widely used methods, such as chemiluminescence. From easier multiplexing to brighter fluorophores to easier method development, learn about the many advantages of fluorescent western blotting.

In 2016, we published a wide variety of general interest articles, customer testimonials, tips, protocols, videos, product highlight articles, and technical and application notes. Here are the ten articles you found the most interesting in 2016.

Introduce students (and teachers) to the concepts of photosynthesis and cellular respiration in the context of how these processes evolved and how they affect our daily lives.

Striving for efficiency in workflow is not a new concept. Automation and use of smart technologies in industries such as automotive and shipping, and services like USPS and UPS, have drastically changed the way they function today not just with innovation but with personalization. Pharma is beginning to understand the need for adopting personalized workflow as well. Now, what can Pharma learn from these industries and how can it apply it to the industry?

In this multi-part series on assessing the health of your cells, we review different factors to be considered in your assessments such as cell viability, proliferation, apoptosis, and autophagy. The first part covers the methods for assessing viability and proliferation and their advantages, and discusses some common considerations.

Striking a balance between encouraging innovation and allowing access to knowledge is not simple. Allowing patents for modifications of naturally occurring organisms and cells pose a particular challenge to the scientific community. Adding to the complexity is the variations in regulations between countries. This article discusses these issues with specific examples in biotechnology and biomedical fields.

How can we easily identify biomarkers for different immune cell types? Refer to this color-coded poster for quick and simple identification of human lineage biomarkers.