Epigenetics

RNA sequencing (RNA-Seq) is a fundamental technique for transcriptome profiling, facilitating the detection of gene expression changes across sample groups. Traditional RNA-Seq of complex tissues, however, is not capable of deciphering the unique biological processes that take place within each cell. As such, single-cell RNA-Seq (scRNA-Seq) has emerged for the analysis of RNA molecules from individual cells, uncovering detailed insights that are unobtainable through bulk RNA-Seq.

Gain access to high-performance chromatin profiling to unravel the complexities of cellular heterogeneity, differentiation, and disease-specific alterations in gene regulation. With single-cell ATAC-seq (assay for transposase-accessible chromatin using sequencing), you can delve into the gene regulatory landscape of individual cells, unlocking invaluable insights into the epigenomic mechanisms that shape their behavior.

scATAC-seq is a powerful tool for studying cancer cell heterogeneity. Watch this webinar to see how scATAC-seq can deliver greater insights to your research.

Bedtime stories in Dr David Schaffer’s — one of today’s pioneers in stem cell research — childhood home were often not standard fairy tales. With both parents in careers as biomedical researchers (his mother in drug development and clinical trials for a major pharmaceutical company and his father, in cardiovascular research and a pharmacology professor) much of the conversation as far back as Schaffer can remember centered on biology and science.

EpiQ chromatin analysis kit is a novel epigenetics research tool for the quantitative assessment of chromatin structure in cultured cells. By combining in situ chromatin digestion, genomic DNA purification, and real-time PCR, the chromatin state for several gene promoters can be studied simultaneously.