Nuvia aPrime Banner Bioradiations Bio-Rad
ArticlesChromatographyFeatured StoriesTechnical Reports

Purification of Antibodies with Nuvia aPrime 4A Hydrophobic Anion Exchange Resin

— August 13, 2019
2k 2
Our new hydrophobic anion exchange mixed-mode resin, Nuvia aPrime 4A, has been developed to overcome existing challenges in antibody purification. See how we purified an acidic and basic antibody through bind-elute and flow-through modes of purification, respectively, and helped to improve process productivity and economy.
READ MORE →
PPB-Nuvia-aPrime-Webinar
ChromatographyPast WebinarsWebinars

A New AEX Mixed-Mode Chromatography Resin for High Selectivity and Recovery

— June 11, 2019
712 0

Presented by: Xuemei He, PhD, R&D Manager, Chromatography Media Chemistry, Bio-Rad Laboratories

View on demand

This webinar highlights the properties of Bio-Rad’s newest hydrophobic AEX chromatography resin, Nuvia aPrime 4A, which is designed to facilitate selective and reversible binding of target molecules for higher purity and recovery over traditional chromatography resins.

READ MORE →
Discover Our Capabilities
ArticlesCell Biology VideoChromatography VideoElectrophoresis/Western Blotting VideoReal-Time qPCR/PCR Video

Discover Our Capabilities

— April 10, 2019
593 0
From flow cytometry to chromatography to western blot imaging to PCR plastics, learn more about Bio-Rad and see what’s possible in your research.
READ MORE →
Stop Compromising between High Yield and High Purity in Downstream Purifications
ArticlesChromatographyFeatured Stories

Stop Compromising between High Yield and High Purity in Downstream Purifications

— March 12, 2019
1.1k 0
When it comes to downstream protein purifications, does it feel like you’re in a constant tug of war between high yield and high purity? With Bio-Rad’s Nuvia aPrime 4A Resin, you don’t have to choose. With both ion exchange and mixed-mode properties, see how the resin is able to deliver simultaneous purity and yield, for even difficult-to-purify proteins.
READ MORE →
Changing the Treatment Landscape with the Development of Biologics
ArticlesChromatographyFeatured Stories

Changing the Treatment Landscape with the Development of Biologics

— February 13, 2019
1.3k 0
Biologics are transforming the healthcare landscape and bringing us closer to the realization of personalized solutions to our health problems. Learn about what biologics are and how protein purification plays a key role in their overall success as a therapeutic.
READ MORE →
A Model System for Fast Screening of Optimal Protein Purification Conditions
ArticlesChromatographyTechnical Reports

A Model System for Fast Screening of Optimal Protein Purification Conditions

— January 9, 2019
1.9k 5
See how you can efficiently reduce identification of optimal protein purification conditions from five days to just 18 hours. All you need is a DOE model and the Multivariable Scouting tool and automation abilities of the NGC Chromatography System.
READ MORE →
ArticlesChromatographyTechnical Reports

Single-Step Influenza and Dengue Virus Purification with Mixed-Mode CHT Ceramic Hydroxyapatite XT Media

— October 9, 2018
1.5k 3
See how you can use CHT XT Mixed-Mode Media to recover over 75% of your virus in a single purification step. All this while reducing contaminating proteins by over 90% and removing over 60% of dsDNA. Get simple, fast, and reproducible viral purification with CHT XT.
READ MORE →
Nuvia HP-Q
ChromatographyPast WebinarsWebinars

Large Biomolecule Purification with a New High-Performance Anion Exchange Resin

— October 9, 2018
510 0

Presented by: Hana Kim, PhD, Global Product Manager, Process Chromatography
Jiali Liao, PhD, Principal Scientist, Process Chromatography

View on demand

Learn about Nuvia HP-Q Resin, a new rigid bead engineered with large pores and optimized surface extenders to deliver both high binding capacity and high recovery at high flow rates. It is ideal for large molecule purification, including plasma proteins, viruses, and VLPs.

READ MORE →
CHT XT
ChromatographyPast WebinarsWebinars

A New Mixed-Mode Media for Downstream Purification

— October 9, 2018
393 0

Presented by: Daniel Yoshikawa, PhD, Global Product Manager, Process Chromatography
Mark A. Snyder, PhD, R&D Applications Manager, Process Chromatography

View on demand

Watch this webinar to learn about a new mixed-mode chromatography media used to purify biomolecules at process scale. It delivers unique selectivity and robust, uniformly sized beads with excellent pressure-flow properties ideal for bioprocess applications.

READ MORE →
Minimize On-Column Aggregation during mAb Purification
ArticlesChromatographyProtocols and Tips

Got Purification Troubles?

— August 15, 2018
906 0
Use our interactive infographic to find out how your resin-of-choice fares in on-column aggregate formation during monoclonal antibody purification. And find out what you can do to minimize these on-column aggregates.
READ MORE →