ArticlesProtein Interaction AnalysisProtocols and Tips

Analyzing Binding Kinetics with Surface Plasmon Resonance Complemented with Direct Mass Spectrometry on the Same Sensor Chip

Surface Plasmon Resonance (SPR) is an optical phenomenon that is used for the label-free analysis of the binding of any two molecules in real-time.
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ArticlesProduct HighlightsReal-time qPCR/PCR

New Premium Hard-Shell Microplate for Applied Biosystems 7500 Fast and ViiA 7 Fast Real-Time PCR systems

Bio-Rad introduces new Hard-Shell 96-well Semi-skirted low profile PCR plates for optimal performance with a variety of real-time PCR systems.
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ArticlesFeatured StoriesGeneral Interest

Top Stories of 2012 – BioRadiations Year in Review

Bioradiations.com, the online technical resource for Bio-Rad customers, has been offering a variety of research tips and protocols, customer stories and testimonials, and in-depth technical reports throughout the year. Here are the highlights of what we presented in the year 2012.
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ArticlesProduct HighlightsReal-time qPCR/PCR

New Roche LightCycler 480 Hard-Shell® Plate That Does Not Warp During Thermal Cycling

Stability during thermal cycling and uniformity of wells are important features in any PCR plate for obtaining reliable results. Bio-Rad’s new Hard-Shell® plates are stable, prevent warping and shrinkage, and are designed for optimal thermal transfer and recovery of samples.
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ArticlesCell BiologyProduct Highlights

Bio-Rad’s New S3™ Cell Sorter Automates and Simplifies Cell Sorting

Cell sorting is a complex and expensive process, with complicated steps requiring training. Bio-Rad’s new S3™ cell sorter is compact, easy to use, automated, affordable, and provides exceptional sort purity and yield results.
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ArticlesProduct HighlightsReal-time qPCR/PCR

New CFX96 Touch™ Deep Well Real-Time PCR Instrument Enables Large-Volume qPCR Reactions

Large sample volumes may sometimes be needed to conduct gene expression studies. Bio-Rad’s new CFX96 Touch Deep Well™ real-time PCR detection system can run sample volumes up to 125 µl and can discriminate up to five targets simultaneously.
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ArticlesProduct HighlightsReal-time qPCR/PCR

CFX Qualification Plate — A Reliable Performance Verification Tool for any CFX Real-Time PCR System

Verifying the performance of your real-time PCR system is crucial to obtaining reliable data from your experiments. Bio-Rad’s new CFX qualification plate comes with a quick and easy protocol that provides reliable performance verification of any real-time qPCR system.
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ArticlesReal-time qPCR/PCRTechnical Reports

PrimePCR™ Pathway Analysis: Pathway Curation and Real-Time PCR Panel Design Strategy

Pathway analysis is an efficient approach for studying a large number of related gene targets in a single experiment. Bio-Rad Laboratories and Thomson Reuters, a leading provider of system biology tools, have partnered to provide predesigned pathway panels for gene expression analyses using real-time qPCR. This tech report describes how Bio-Rad’s PrimePCR™ pathway panels were curated and designed using a ranking strategy developed by Thomson Reuters.
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ArticlesProduct HighlightsReal-time qPCR/PCR

New Semi-Automated Heat Sealer Delivers Consistent and Reliable PCR Plate Sealing

The PX1 PCR Plate Sealer efficiently seals microplates used in thermal cycling. This heat sealing method consistently delivers reliable data by helping eliminate sample evaporation during PCR.
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ArticlesCustomer StoriesElectrophoresis/Western Blotting

TGX Stain-Free™ Precast Gels Facilitate LDL Research on Potential New Drug Targets

When Dr. Fred Bauzon started his research, he worked with bioinformatics specialists to functionalize suitable gene candidates based on their expression levels with HMGCR transcript levels. All his experiments demonstrated a reduction in low-density lipoprotein receptor protein (LDLR) and candidate gene protein levels after the candidate gene was silenced. Here Bauzon discusses how TGX Stain-free precast gels have aided his research toward future drug targets for the therapeutic control of LDL uptake.
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