ArticlesCustomer StoriesFeatured StoriesReal-time qPCR/PCR

Using PrimePCR™ Gene Expression Assays to Understand Breast Cancer Metastasis

Tumor metastasis is a complex process. It requires the ability of the cancer cells to invade their surroundings and travel to distant sites and survive. Dr. Traci Lyons studies the mechanism of COX-2 functioning in the metastasis of breast cancer cells. Find out how Dr. Lyons used Bio-Rad’s PrimePCR™ Assays to confirm COX-2 knockdown at the mRNA level.
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ArticlesCustomer StoriesFeatured StoriesReal-time qPCR/PCR

Too Many Questions, Too Little Sample: Developing a Real-Time PCR Workflow for Monitoring Gene Expression in Limited Samples

Traditional real-time PCR workflows often limit the number of genes that can be studied, especially when sample amounts are small. A new workflow now allows Mark Kibschull of the Lunenfeld-Tanenbaum Research Institute in Toronto to track the expression of hundreds of genes using a fraction of the starting material required by traditional methods.
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ArticlesCustomer StoriesEducation CornerGeneral Interest

3 Moments of Inquiry with Bio-Rad’s pGLO™ Transformation and Inquiry for AP Biology: A ThINQ! Investigation Kit

“Inquiry-based” is the new buzzphrase in science education. But what do these learning practices look like on the ground? Visit one high school in Southern California and find out about this new approach to teaching science.
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ArticlesCell BiologyCustomer StoriesFeatured Stories

Investigating Cancer Stem Cells with the S3™ Cell Sorter

The Cancer Stem Cell model proposes that a special group of dormant cells in the cancer population plays a key role in tumor development and growth, as well as regeneration following treatment. Find out how researchers Stacy Blain and Danielle Joseph are using the S3 Cell Sorter in studying potential cancer stem cells for multiple myeloma.
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ArticlesCustomer StoriesDroplet Digital PCR (ddPCR)

Protecting Coastal Ecosystems with Droplet Digital™ PCR

Who’s watching over swimmer safety at America’s beaches? Go inside one agency tasked with pioneering new methods for water quality monitoring, and see how its scientists are employing Droplet Digital PCR technology to check coastal waters for harmful pathogens.
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ArticlesCustomer StoriesElectrophoresis/Western BlottingFeatured Stories

Telling the Story of Western Blots with the ChemiDoc Touch Imaging System

For a long time X-ray film has been the standard for imaging western blots, but this method has its limitations. Find out how 3 researchers are using the digital tools offered by the new ChemiDoc Touch Imaging System to beat these limitations and improve their blot images.
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ArticlesCustomer StoriesDroplet Digital PCR (ddPCR)

Genomic Variation Analysis with Droplet Digital PCR: Success Stories

Researchers are having success applying Droplet Digital PCR (ddPCR™) technology across many different fields. Here are two such success stories, one involving the application of ddPCR in detecting mutations in iPS cells, the other in predicting allele-specific variation in human brain development.
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ArticlesChromatographyCustomer Stories

Unlocking the Structures of Natural Killer Cell Receptors with the NGC™ Chromatography System

Structural biologist Petr Novák employs the latest techniques to model natural killer cell receptor molecules, research that may one day result in powerful therapies to treat cancer and infections. Go inside the fascinating world of structural characterization and find out how Novák has integrated the NGC™ chromatography system into his effort to visualize these molecules in vivid detail.
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ArticlesCustomer StoriesDroplet Digital PCR (ddPCR)Featured Stories

Transforming Cancer Research: Droplet Digital PCR Plays Integral Role at Fred Hutchinson Cancer Research Center

Droplet Digital PCR has major implications for cancer studies, where the ability to accurately measure biomarkers may result in important insights into cancer genesis and progression. Find out about new findings on micro RNA and Tumor Infilitrating Lymphocytes made possible by ddPCR technology.
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ArticlesBio-Plex Multiplex AssaysCustomer Stories

Profiling Dynamic Cancer Drug Responses with BioMarker Strategies, LLC and the Bio-Plex® Multiplex Immunoassay System

In an age of personalized medicine, getting the most out of highly targeted cancer therapies takes finding the best molecular targets for each patient. BioMarker Strategies LLC, a small startup, has been developing an innovative method to do this by modeling oncogenic pathway responses, but they needed to accurately measure the levels of phosphoproteins resulting from the activation of these genes. Learn how they are using the Bio-Plex multiplex immunoassay system to accurately quantify the proteins and generate functional signaling profiles for these oncogenes.
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