Cell Biology

Even though antibodies are central to basic research as well as drug development and diagnostics, concerns with antibody validation remain high, and finding an antibody that works well for a specific application can be quite a challenge. Use these tips to select the best antibodies for your application.

Cell analysis is a crucial first step in many experiments so a reliable, flexible, and quick cell analyzer that produces high-resolution, reproducible results is what every lab needs. See how the ZE5™ Cell Analyzer can help improve the quality of your cell analysis experiments, instill confidence in your results, and shorten the time to publish.

Stem cells possess the remarkable potential to self-renew and to differentiate into many different types of cells. Due to their unique ability to regenerate, they are being used in regenerative medicine and offer great hope for treating diseases such as diabetes and heart disease. However, since stem cells represent a rare population of cells, they are not always easy to study. See how the simplicity, efficiency, and flexibility of cell sorting is making it possible to isolate pure populations of stem cells for downstream analyses.

The power to edit a gene is the power to change its function, and with it the biology of a cell. From generating novel cell lines and better animal models for the discovery and preclinical phases of therapeutic research to actually creating a therapeutic itself, CRISPR gene editing is allowing science to advance rapidly. See how enrichment and cell sorting can help generate edited cells faster and more reliably.

In this podcast, you will learn about the history of bromodeoxyuridine (BrdU) and how it was established as a popular tool for neurogenesis research. Gain insight into the latest BrdU-related findings and get five practical tips for controlling your BrdU labeling experiments.

The eukaryotic cell cycle is an evolutionarily conserved process that results in the replication of cells. Read this mini review to better understand the eukaryotic cell cycle and get an overview of common molecular techniques used to evaluate proliferating cells.

In this fourth and final part of the series on assessing the health of your cells, we review the different stages of necroptosis, see how it differs from apoptosis, and learn about the various methods of assessing cellular necroptosis.

Bio-Rad’s new ZE5 Cell Analyzer is a game-changing cell analyzer that was designed with direct input from scientists and flow core labs. Karen Helm runs the flow core facility at the University of Colorado Cancer Center and was one of the experts consulted. See how ZE5 is helping her flow core users do better science.

Part III of our cell health series describes the three main autophagy mechanisms and reviews the various methods for assessing macroautophagy and autophagic flux in cells.

Monocytes play key roles in mediating innate and adaptive immune responses. Here is an overview of the types, functions, process of recruitment, and the role of monocytes in disease.