ArticlesDrug Discovery and DevelopmentTechniques

Saving Lives: Innovative Therapeutic Applications of Ion Exchange Resins

Although chromatography resins are usually thought of as tools to purify medicines, groundbreaking treatments now utilize resin beads as an integral component of the therapy itself. These therapies are essential for treating certain cancers and inflammatory disorders.
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ArticlesDrug Discovery and DevelopmentResearch Highlights

The Journey from Lab to Clinic: Zolgensma, the First Gene Therapy Treatment for Spinal Muscular Atrophy (SMA)

Translational research bridges the gap between scientific discoveries and real-world applications, transforming scientific breakthroughs into life-changing therapies. Success in this endeavor hinges on several factors, including collaboration between scientists and clinicians. A notable example of this is the approval of Zolgensma, a gene therapy for spinal muscular atrophy (SMA), which marked a significant milestone in the field of translational research.
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ArticlesCell BiologyDroplet Digital PCR (ddPCR)

Vive la Différence: The Beauty of Diversity in Life, Life Science, and Flow Cytometry

The differences between us are what makes life interesting, and diversity in a group that shares a common goal can lead to many benefits. Here we examine the similarities and differences between researchers using flow cytometry for academic research and those using it for drug discovery. We outline the challenges they face and learn that they share a common goal as well as a common solution.
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ArticlesElectrophoresis/Western Blotting

Compliance at Your Fingertips: Using Image Lab Touch Software for Digital Imaging in Regulated Environments

Maintaining compliance while leveraging advanced digital imaging technologies can be a daunting task. Luckily, Bio-Rad Image Lab Touch Software takes this challenge head-on by offering a seamless solution for digital imaging. Learn how Image Lab Touch Software integrates with Bio-Rad imaging systems to support researchers in meeting stringent regulatory requirements, ensuring data integrity and security without compromising efficiency or ease of use.
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Cell Biology VideoGeneral InterestGeneral Interest VideoVideos

Biotherapeutic Antibody Discovery at Bio-Rad’s New Center for Excellence

The Pioneer Platform features one of the largest functional antibody libraries available, utilizing SpyLock technology for rapid prototyping and screening of hundreds of bispecific antibodies, and TrailBlazer technology for efficient antibody format conversion. Together, these services provide a comprehensive and streamlined solution for researchers seeking to develop innovative biotherapeutic therapies.
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ArticlesReal-time qPCR/PCR

Maximizing PCR and qPCR Throughput with Automated Solutions

Automation in PCR and qPCR processes is revolutionizing laboratory workflows in regulated environments like biopharma and CROs. By enhancing efficiency, reducing manual errors, and ensuring compliance with regulatory standards, automation allows labs to scale operations and increase throughput without compromising data quality. Here we show the range of Bio-Rad products that are compatible with automated solutions for PCR and qPCR workflows.
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ChromatographyFeatured WebinarsWebinars

Evaluation of a New Multimodal Anion Exchange Resin for Emerging Biotherapeutic Process Challenges

Nuvia wPrime 2A Resin has MMAEX functionality with a weak anion exchanger. See data showing improved mAb and bsAb purification compared to traditional resins.
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Cell BiologyFeatured WebinarsWebinars

Cytometry in Drug Discovery: An Introduction to Regulation, Standardization, and Productivity

Many researchers learn flow cytometry in academia, but find new challenges in the commercial sector. In this webinar, learn about regulatory issues and more.
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ArticlesChromatographyTechniques

6 Essential Considerations for Choosing Your Chromatography Resin

Choosing the right chromatography resin is a complex and critical decision that can significantly impact the success of your downstream purification workflow, whether for preparative or analytical applications. To make an informed choice, you must consider the scientific principles of the process, practical implications for your specific application, and attributes of the manufacturer.
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ArticlesNext-Generation Sequencing

What a Single Cell Can Tell You: Exploring Gene Expression and Regulation of Single Cells

RNA sequencing (RNA-Seq) is a fundamental technique for transcriptome profiling, facilitating the detection of gene expression changes across sample groups. Traditional RNA-Seq of complex tissues, however, is not capable of deciphering the unique biological processes that take place within each cell. As such, single-cell RNA-Seq (scRNA-Seq) has emerged for the analysis of RNA molecules from individual cells, uncovering detailed insights that are unobtainable through bulk RNA-Seq.
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